Natural Health Journals


A natural precursor to steroid hormones, pregnenolone in the body is converted into hormones such as DHEA, testosterone, progesterone, and estrogen. A rat study in 1992 indicating its effectiveness as a cognitive enhancer piqued the interest of smart-drug users, but no human studies have been completed to date. As with all other hormones, the long-term effects of pregnenolone are not yet well understood; and its claims as a cognitive enhancer are mostly unsubstantiated by anything other than anecdotal evidence and the 1992 rat study.


Hormone supplements may help boost your mood and energy levels, but their long-term effects are not yet well understood. And if you already have optimal levels, some hormones may be dangerous. Because it’s difficult to assess your own condition, we suggest that you take hormone supplements only under the supervision of a doctor.


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